Thermo Fisher Scientific CXCL13 Polyclonal Antibody
CXCL13 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, IHC, ICC 등 다양한 응용에 사용 가능. Human 반응성 검증 완료. 항원 친화 크로마토그래피로 정제. 4°C 또는 -20°C에서 안정적으로 보관 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000–1:10,000 | View 1 publication |
| Immunohistochemistry (IHC) | – | View 3 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 | – |
| Immunohistochemistry (Frozen) (IHC (F)) | – | View 1 publication |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 | – |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human |
| Published Species | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a region within amino acids 45–109 of Human BCA1 (CXCL13) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.21 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2546303 |
Product Specific Information
- Recommended positive control: CXCL13-transfected 293T cells
- Store product as a concentrated solution. Centrifuge briefly before opening the vial.
Target Information
CXCL13 (also known as BCA-1 and Angie) is a small chemokine highly expressed in secondary lymphoid organs. It promotes migration of B lymphocytes (B-1 and B-2) to follicles in spleen, lymph nodes, and Peyer’s patches. Produced mainly by macrophages, including large peritoneal macrophages, Kupffer cells, and lung macrophages (CD11c+ and CD11c−).
The receptor for CXCL13 is CXCR5 (also known as BLR-1), expressed on B cells, Tfh cells, and some memory T cells. CXCL13 is implicated in chronic lymphocytic leukemia (CCL) and serves as a plasma biomarker for germinal center activity and broadly neutralizing antibody generation against HIV.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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