Thermo Fisher Scientific Omburtamab Recombinant Mouse Monoclonal Antibody

Applications

Tested Dilution

Publications

ELISA (ELISA)

1:5,000-1:10,000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1, kappa

Expression System

CHO cells

Class

Recombinant Monoclonal

Type

Antibody

Immunogen

Human CD276/B7-H3/B7RP-2

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

3.19 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.5

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2911359

Product Specific Information

Endotoxin level < 0.01EU/µg by LAL method

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 °C for one week. Store at -20 to -80 °C for twelve months from the date of receipt.

Target Information

Omburtamab is a monoclonal antibody that targets the B7-H3 antigen expressed in a variety of human solid tumors. Omburtamab (alias: 8H9, former name: Burtomab) is a monoclonal antibody that is linked to a radioisotope and can bind to the B7-H3 antigen on the surface of neuroblastoma cells. It is injected directly into the cerebrospinal fluid to bypass the blood-brain barrier and accurately target neuroblastoma in the central nervous system to avoid damage to other tissues (such as learning disabilities and developmental delays often caused by conventional radiotherapy outside the brain).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.