Thermo Fisher Scientific PSG1 Monoclonal Antibody (5C6G7)
인간 PSG1 단백질을 인식하는 마우스 단일클론 항체로, Western blot, Flow cytometry, ELISA에 사용 가능. 고순도 Protein G 정제, 1 mg/mL 농도의 액상 제품. 연구용으로 면역반응 조절 및 태반 관련 단백질 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Flow Cytometry (Flow) | 1:200–1:400 |
| ELISA | 1:10,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 5C6G7 |
| Immunogen | Purified recombinant fragment of human PSG1 (aa 250–419) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C (short term). For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2898523 |
Product Specific Information
This antibody has been tested in indirect ELISA.
Target Information
Human pregnancy-specific glycoproteins (PSG) are a group of closely related secreted glycoproteins highly expressed in placental syncytiotrophoblast cells of fetal origin. PSG are commonly found in tumors of trophoblast origin such as hydatidiform mole and choriocarcinoma. They represent the most abundant fetal protein in maternal blood at term.
The eleven human PSG genes (PSG1–PSG11) form, together with the carcinoembryonic antigen (CEA)-related cell adhesion molecule (CEACAM) genes, the CEACAM gene family. PSG stimulates secretion of TH2-type cytokines from monocytes, with CD9 identified as the monocyte receptor for murine PSG17. PSG are believed to modulate the maternal immune system during pregnancy, protecting the semiallotypic fetus from rejection.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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