Thermo Fisher Scientific TG Monoclonal Antibody (OTI1C8), TrueMAB
인간 Thyroglobulin(TG)을 인식하는 단클론 항체로, IHC(P)에서 1:150 희석으로 검증됨. 마우스 IgG1 아이소타입, 비결합형 동결건조 형태. 친화 크로마토그래피로 정제되었으며, -20°C에서 보관. 연구용으로만 사용 가능.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): Tested dilution 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1C8 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 20–358 of human TG produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Human thyroglobulin (hTg) is a high molecular weight glycoprotein (~605 kDa) present in thyroid follicular cells. It is essential for the uptake, incorporation, and regulated biosynthesis of thyroid hormones T4 and T3.
Anti-thyroglobulin autoantibodies are associated with autoimmune thyroid diseases such as Hashimoto thyroiditis and Graves disease, with the highest levels found in Hashimoto thyroiditis. These antibodies are also characteristic of thyroid cancer and can be used for patient follow-up.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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