Thermo Fisher Scientific TFB1M Monoclonal Antibody (OTI10H8), TrueMAB
인간 TFB1M 단백질(아미노산 116-346)을 인식하는 Mouse IgG1 단일클론 항체. Western blot에 최적화되어 있으며, 무보존제 리오필라이즈 형태로 제공. 연구용으로만 사용 가능하며, 미토콘드리아 유전자 발현 연구에 적합.
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Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI10H8 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 116–346 of human TFB1M produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
The TFB1M protein is a dimethyltransferase that methylates the conserved stem loop of mitochondrial 12S rRNA.
It is part of the basal mitochondrial transcription complex and is essential for mitochondrial gene expression.
Its methylation and transcriptional activities are independent.
Gene variations may influence the severity of aminoglycoside-induced deafness.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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