Thermo Fisher Scientific NAV3 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human NAV3. Recombinant protein control fragment (Product #RP-94970). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:NAV3,uniProtId:Q8IVL0-1,ncbiNodeId:9606,antigenRange:898-982,antigenLength:2385,antigenImageFileName:PA5-56931_NAV3_Q8IVL0-1_Rabbit.svg,antigenImageFileNamePDP:PA5-56931_NAV3_Q8IVL0-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.3 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2644489

Product Specific Information

Immunogen sequence: STDDLNTTSS VSSYSNITVP SRKNTQLRTD SEKRSTTDET WDSPEELKKP EEDFDSHGDA GGKWKTVSSG LPEDPEKAGQ KASLS

Highest antigen sequence identity to the following orthologs: Mouse - 82%, Rat - 85%.

Target Information

Neuron navigator 3 (NAV3), also known as pore membrane and/or filamentinteracting-like protein 1 (POMFIL1), unc-53 homolog 3 (unc53H3) or STEERIN3, is a 2,385 amino acid protein that localizes to the nuclear outer membrane and plays a role in neuron regeneration. Existing as three alternatively spliced isoforms, Neuron navigator 3 is highly expressed in adult and fetal brain and is found at moderate to low levels in ovary, lung, testis, placenta and heart. Neuron navigator 3 is thought be involved in the regulation of IL-2 production and contains one CH (calponin-homology) domain, three N-terminal hydrophobic domains, multiple N-glycosylation sites, three ATP/GTP-binding A motifs (P loops) and several phosphorylation sites.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.