Thermo Fisher Scientific MLK4 Recombinant Rabbit Monoclonal Antibody (HL2234)
Human MLK4 단백질을 인식하는 Recombinant Rabbit Monoclonal Antibody로, Western Blot 및 Immunocytochemistry에 사용 가능. HEK293 세포에서 발현된 HL2234 클론, Protein A 정제, 2 mg/mL 농도. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB): Assay-dependent
- Immunocytochemistry (ICC/IF): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | HL2234 |
| Immunogen | Recombinant protein encompassing a sequence within the C-terminus region of human MLK4 (exact sequence proprietary) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3092942 |
Target Information
MLK4 (Mixed Lineage Kinase 4) belongs to the superfamily of MAP kinase kinases (MAP3K1) containing both serine/threonine and tyrosine kinase activity in their catalytic domains.
This kinase family includes an N-terminal SH3 domain, a kinase domain, a leucine zipper region, and a CDC42/RAC-interactive binding (CRIB) motif, with divergent C-terminal regions.
MLK4 is highly expressed in kidney and pancreas and acts as a negative regulator of TLR4. It does not activate JNK1/MAPK8, p38/MAPK14, or ERK2/MAPK1 pathways.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: MA5-50448_MLK4_Q5TCX8-1_Rabbit_PDP.jpeg, MA5-50448_MLK4_Q5TCX8-1_Rabbit.svg)
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