Thermo Fisher Scientific CRMP1 Recombinant Rabbit Monoclonal Antibody (23GB3480)
CRMP1 단백질을 인식하는 재조합 토끼 단클론 항체로, 인간 시료에 반응합니다. Western blot, ICC/IF, Flow cytometry에 적합하며 고순도 친화 크로마토그래피로 정제되었습니다. 액상 형태로 제공되며, 안정적인 저장을 위해 PBS와 글리세롤을 포함합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:5,000 |
| Immunocytochemistry (ICC/IF) | 1:1,000 |
| Flow Cytometry (Flow) | 1:2,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293F |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 23GB3480 |
| Immunogen | A synthetic peptide of human CRMP1 (500–572AA) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice (domestic); Dry ice (international) |
Target Information
Collapsin-response mediator proteins (CRMPs) are highly expressed in the developing brain where they play major roles in axonal outgrowth, neurite differentiation, and apoptosis. Their continued expression in areas of high synaptic remodeling such as the cerebellum, hippocampus, and the olfactory system suggests that these proteins may also be involved in adult brain plasticity.
CRMP-1 was initially identified as a dihydro-pyrimidinase expressed exclusively in the brain; later studies have shown that it is involved with neurotrophin (NT) 3-induced neurite formation and outgrowth. CRMP-1 localization switches from axonal to somatodendritic when neurons reach functional maturity, suggesting involvement in early neuronal differentiation and later processes related to survival or death of newly generated neurons.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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