Thermo Fisher Scientific BAG5 Monoclonal Antibody (OTI5F1), TrueMAB
BAG5 단백질을 인식하는 Mouse monoclonal antibody로 Western blot에 적합합니다. Human, Mouse, Rat 시료에 반응하며, 동결건조 형태로 제공됩니다. PBS 버퍼(8% trehalose) 내 보관하며, -20°C에서 보관 권장. 연구용으로만 사용 가능합니다.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5F1 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 290–440 of human BAG5 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
BAG-5 protein is hypothesized to induce the death of nigral neurons through its predicted interaction with hsp70, leading to increased protein aggregation and cell death by disinhibition of hsp70’s anti-apoptotic function.
BAG-5 may play an important role in neuronal death mechanisms and could act as a modulator of the hsp70/hsp40 chaperone axis or interact with other BAG-containing proteins via BAG-BAG heterodimerization.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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