Thermo Fisher Scientific CSN7b Polyclonal Antibody
Rabbit 유래의 CSN7b 폴리클로날 항체로 Western blot에 적합합니다. 인간 단백질의 225–264번 잔기 영역을 면역원으로 사용하였으며, 마우스 및 소 단백질과 교차 반응이 예측됩니다. 액상 형태로 제공되며 4°C에서 보관합니다.
- 카탈로그번호
- A300044Ax (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific CSN7b Polyclonal Antibody
Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:10,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 225 and the C-terminus (residue 264) of human constitutive photomorphogenic homolog subunit 7B |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Mouse and Bovine
Target Information
Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes.
The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decreased Ubl ligase activity of SCF-type complexes such as SCF, CSA, or DDB2.
The complex is also involved in phosphorylation of p53/TP53, JUN, I-kappa-B-alpha/NFKBIA, ITPK1, and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases.
CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.