Thermo Fisher Scientific Fodrin/Alpha Spectrin II (SPTAN1)/NEAS Monoclonal Antibody (SPTAN1, 3352)
인간 SPTAN1 단백질을 인식하는 마우스 단클론 항체로, 면역조직화학 및 펩타이드 배열 분석에 적합합니다. 단백질 A/G 정제, PBS 용액 형태이며 보존제 무첨가. 세포골격 연구 및 신경 관련 단백질 분석에 활용 가능.
- 카탈로그번호
- 6709-MSM2-P1ABX
- 판매단위
- pk
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Thermo Fisher Scientific Fodrin/Alpha Spectrin II (SPTAN1)/NEAS Monoclonal Antibody (SPTAN1, 3352)
Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1–2 µg/mL
- Peptide Array (Array): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2c, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | SPTAN1, 3352 |
| Immunogen | Recombinant fragment of human SPTAN1 protein (around aa 2351–2475) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Immunohistochemistry (PFA fixed): incubate antibody for 30 min at room temperature.
Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA (pH 9.0) for 45 min at 95°C, followed by cooling at room temperature for 20 min.
Target Information
SPTAN1 (spectrin alpha chain, non-erythrocytic 1) is part of the spectrin family of filamentous cytoskeletal proteins.
Spectrins serve as scaffold proteins that stabilize the plasma membrane and organize intracellular organelles.
They are composed of alpha and beta dimers forming tetramers linked in a head-to-head arrangement.
SPTAN1 is also involved in DNA repair and cell cycle regulation.
Mutations in this gene cause early infantile epileptic encephalopathy-5.
Alternate splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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