Thermo Fisher Scientific ISCU Monoclonal Antibody (OTI8H2), TrueMAB
Human ISCU 단백질을 표적으로 하는 Mouse IgG1 단일클론 항체로 Western blot에 적합. 동결건조 형태로 제공되며, PBS 및 trehalose buffer 포함. 연구용으로 사용되며, Fe-S 클러스터 단백질 연구에 유용.
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Applications
- Western Blot (WB)
Tested Dilution
- 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI8H2 |
| Immunogen | Full length human recombinant protein of human ISCU produced in E.coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Iron-sulfur (Fe-S) clusters are essential cofactors for several mitochondrial and cellular enzymes. They are formed through steps involving cysteine desulfurases, iron donors, chaperones, and scaffold proteins.
The ISCU gene encodes two isoforms (ISCU1 and ISCU2) of the Fe-S cluster scaffold protein. Mutations in this gene are associated with myopathy characterized by severe exercise intolerance and myoglobinuria.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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