Thermo Fisher Scientific EDD1 Polyclonal Antibody
EDD1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, IP에 사용 가능하며 인간 시료에 반응. 항원 친화 크로마토그래피로 정제된 액상 제품으로 4°C에서 보관.
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Thermo Fisher Scientific EDD1 Polyclonal Antibody
Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:2,000 |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residues 600 and 650 of human E3 Ubiquitin Protein Ligase, HECT domain containing, 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Tris citrate/phosphate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt.
- For IHC: Epitope retrieval with citrate buffer (pH 6.0) is recommended for FFPE tissue sections.
- Based on 100% sequence identity, this antibody is predicted to react with Rat.
Target Information
EDD (E3 identified by Differential Display) is a progestin-regulated gene isolated from T-47D human breast cancer cells. Based on sequence homology, EDD is a human homolog of the Drosophila hyperplastic discs (hyd) gene, a tumor suppressor required for imaginal disc growth control.
EDD contains a HECT domain at the carboxy terminus. HECT domain-containing proteins act as ubiquitin-protein ligases (E3 enzymes). EDD binds to ubiquitin and may function as an E3 ubiquitin-protein ligase similar to other HECT family proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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