Thermo Fisher Scientific AMPK alpha 2 Polyclonal Antibody, FITC
AMPK alpha 2 단백질을 인식하는 FITC 결합 폴리클로날 항체로, Western blot, IHC, ELISA, IP 등 다양한 응용에 적합. 사람, 생쥐, 랫트 반응성. 에너지 대사 및 인슐린 감수성 연구에 활용 가능.
- 카탈로그번호
- AMPK2-FITC
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific AMPK alpha 2 Polyclonal Antibody, FITC
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (IHC) | 1:50–1:250 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 480–530 on rat 5'-AMP-activated protein kinase catalytic subunit alpha-2 protein |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, containing 0.5% BSA and 30% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit and non-catalytic beta and gamma subunits. It functions as an energy-sensing enzyme that monitors cellular energy status. Upon activation under metabolic stress, AMPK phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and HMG-CoA reductase (HMGCR), key enzymes in fatty acid and cholesterol biosynthesis. Studies in mouse models suggest that this subunit plays a role in regulating insulin sensitivity and maintaining myocardial energy homeostasis during ischemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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