ELK Biotechnology RARG rabbit pAb
RARG 단백질을 인식하는 토끼 폴리클로날 항체로, WB와 ELISA에 사용 가능. 핵 및 세포질에 위치한 단백질 검출에 적합. 인간 및 생쥐 시료에 반응하며, 고순도 IgG 형식으로 제공. -20°C에서 1년 보관 가능.
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RARG rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | RARG rabbit pAb |
| Applications | WB; ELISA |
| Recommended Dilutions | WB 1:500–2000, ELISA 1:5000–20000 |
| Immunogen | Synthesized peptide derived from human protein (AA range: 360–440) |
| Species Reactivity | Human; Mouse |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 49 kD |
| GeneID (Human) | 5916 |
| Human Swiss-Prot No | P13631 |
| Cellular Localization | Nucleus, Cytoplasm |
| Storage | -20°C / 1 year |
Background
This gene encodes a retinoic acid receptor that belongs to the nuclear hormone receptor family. Retinoic acid receptors (RARs) act as ligand-dependent transcriptional regulators. When bound to ligands, RARs activate transcription by binding as heterodimers to the retinoic acid response elements (RARE) found in the promoter regions of the target genes. In their unbound form, RARs repress transcription of their target genes. RARs are involved in various biological processes, including limb bud development, skeletal growth, and matrix homeostasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
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