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ELK Biotechnology NRBP rabbit pAb
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ELK Biotechnology NRBP rabbit pAb

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NRBP rabbit pAb는 인간 및 마우스 단백질에 반응하는 폴리클로날 항체로 WB와 ELISA에 사용됩니다. 합성 펩타이드로부터 유래된 면역원으로 제작되었으며, 세포질 및 라멜리포디아에 위치합니다. 고순도 IgG 형태로 -20°C에서 1년간 안정적으로 보관 가능합니다.

판매단위
pk
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ELK Biotechnology ES10837-100UL NRBP rabbit pAb, 100UL pk판매 단위 pk ·
재고 확인 필요
402,000원VAT 포함 442,200원
ELK Biotechnology ES10837-50UL NRBP rabbit pAb, 50UL pk판매 단위 pk ·
재고 확인 필요
301,000원VAT 포함 331,100원

ELK Biotechnology · ELK Biotechnology NRBP rabbit pAb

NRBP rabbit pAb

공급업체: ELK Biotechnology
제품명: NRBP rabbit pAb

제품 정보

항목 내용
Applications WB; ELISA
Recommended Dilutions WB 1:500–2000, ELISA 1:5000–20000
Immunogen Synthesized peptide derived from part region of human protein
Species Reactivity Human; Mouse
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band 58 kD
GeneID (Human) 29959
Human Swiss-Prot No Q9UHY1
Storage -20°C / 1 year
Host Rabbit

세포 내 위치 (Cellular Localization)

Cytoplasm, cell cortex, endomembrane system, cell projection (lamellipodium).
Colocalizes with activated RAC3 to endomembranes and at the cell periphery in lamellipodia.

Background

  • Caution: Kinase activity observed in PubMed:11956649 may be due to sample contamination.
  • Domain: The protein kinase domain is predicted to be catalytically inactive.
  • Function: May play a role in subcellular trafficking between the endoplasmic reticulum and Golgi apparatus through interactions with Rho-type GTPases. Binding to NS3 protein of dengue virus type 2 may alter intracellular membrane structure for flaviviral replication.
  • Similarity: Belongs to the protein kinase superfamily; Ser/Thr protein kinase family; contains one protein kinase domain.
  • Subcellular Location: Colocalizes with activated RAC3 to endomembranes and at the cell periphery in lamellipodia.
  • Subunit: Forms homodimer; binds to MLF1, recruiting a serine kinase that phosphorylates itself and MLF1. Phosphorylated MLF1 binds to YWHAZ and is retained in the cytoplasm.
  • Tissue Specificity: Ubiquitously expressed in all tissues examined, with high levels in testis.

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