Thermo Fisher Scientific Phospho-Chk2 (Thr68) Recombinant Rabbit Monoclonal Antibody (Chk2T68-D12), FITC
FITC로 표지된 재조합 토끼 단클론 항체로, 인산화된 Chk2 (Thr68)를 특이적으로 인식합니다. 유세포 분석(Flow Cytometry)에 적합하며, 인간 및 생쥐 시료에서 반응합니다. Protein A/G로 정제된 액상 형태로, 4°C 암소 보관이 권장됩니다.
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Applications
- Flow Cytometry (Flow): 5 µL / 1×10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | Chk2T68-D12 |
| Immunogen | A synthetic phospho-peptide corresponding to residues surrounding Thr68 of human phospho Chk2 |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Purification | Protein A/G |
| Storage Buffer | PBS with 0.20% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2897203 |
Additional Formats
- Unconjugated (MA5-36985)
- APC (MA5-36988)
- PE (MA5-36986)
- Custom conjugation available upon request
Target Information
CHEK2 (CHK2) is a serine/threonine kinase involved in the DNA damage checkpoint pathway. Mutations in CHK2 are associated with various cancers, including Li-Fraumeni syndrome, sarcomas, breast cancer, and brain tumors. CHK2 phosphorylates several cell cycle modulators such as tumor suppressor proteins and BRCA1, contributing to DNA damage response and cell survival regulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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