Thermo Fisher Scientific PSMB10 Monoclonal Antibody (3F8)
PSMB10 단백질을 인식하는 Thermo Fisher Scientific의 마우스 단클론 항체로, Western blot, ICC/IF, ELISA에 사용 가능. 인간 단백질에 반응하며, 비접합 액상 형태로 제공. PBS(pH 7.4) 버퍼에 보관하며, -20°C에서 냉동 보관 권장.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
| ELISA | 3 ng/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3F8 |
| Immunogen | PSMB10 (AAH17198, 1–273 a.a.) full-length recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Protein Sequence:
MLKPALEPRG GFSFENCQRN ASLERVLPGL KVPHARKTGT TIAGLVFQDG VILGADTRAT
NDSVVADKSC EKIHFIAPKI YCCGAGVAAD AEMTTRMVAS KMELHALSTG REPRVATVTR
ILRQTLFRYQ GHVGASLIVG GVDLTGPQLY GVHPHGSYSR LPFTALGSGQ DAALAVLEDR
FQPNMTLEAA QGLLVEAVTA GILGDLGSGG NVDACVITKT GAKLLRTLSS PTEPVKRSGR
YHFVPGTTAV LTQTVKPLTL ELVEETVQAM EVETarget Information
The 20S proteasome is a protease complex responsible for cytosolic protein degradation and generation of peptide ligands for MHC class I molecules. Upon IFN-gamma stimulation, constitutive subunits are replaced by inducible subunits LMP2, LMP7, and MECL-1 (LMP10), forming immunoproteasomes that enhance antigen processing. These subunits can combine into up to 36 unique proteasome subsets, influencing cleavage specificity in protein degradation.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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