Thermo Fisher Scientific LZTR2 Polyclonal Antibody
LZTR2 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC, ICC, ELISA 등 다양한 응용에 적합합니다. Human, Mouse, Rat 시료에 반응하며, Protein A로 정제된 1 mg/mL 액상 제품입니다. TBS buffer(50% glycerol, 1% BSA)로 안정화되어 -20°C에서 보관합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:300 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:200–1:400 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human LZTR2 (amino acids 351–450) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.03% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
LZTR2 (Leucine Zipper Like Transcription Regulator 2), also known as RGPR-p117, is a member of the BTB-kelch superfamily. It was initially identified as a nuclear factor I (NFI) binding protein and a transcriptional regulator of the regucalcin gene. LZTR2 is mainly localized in the cytoplasm but can translocate to the nucleus through protein kinase C signaling following hormonal stimulation.
Recent studies have shown that single nucleotide polymorphisms (SNPs) in LZTR2 are associated with obesity in the Japanese population, similar to associations observed with TMEM18, GNPDA2, BDNF, FAIM2, and MC4R genes in Caucasian populations, suggesting a potential role of LZTR2 in metabolism and obesity risk.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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