Thermo Fisher Scientific MMP-17 Polyclonal Antibody
다중 종 반응성을 가진 Rabbit Polyclonal 항체로, Human, Mouse, Rat 시료에 사용 가능. Western blot, IHC, ICC, ELISA 등 다양한 응용에 적합. MMP17 단백질의 101-200 아미노산 서열을 기반으로 제작. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:400 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human MMP17 (amino acids 101–200) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Matrix metalloproteinase (MMP) family proteins are involved in extracellular matrix breakdown during normal physiological processes such as embryonic development, reproduction, and tissue remodeling, as well as in pathological conditions like arthritis and metastasis. Most MMPs are secreted as inactive proproteins that are activated by cleavage from extracellular proteinases. The MMP17 gene encodes a GPI-anchored membrane-type MMP, distinguishing it from other transmembrane MT-MMPs. This protein is known to activate MMP-2 through cleavage.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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