
Thermo Fisher Scientific TAAR1 Polyclonal Antibody
TAAR1 단백질 검출용 토끼 폴리클로날 항체. Western blot 및 IHC에 적합하며, 마우스 TAAR1 펩타이드를 면역원으로 제작됨. 다양한 조직에서 발현되는 GPCR 연구에 활용 가능. 연구용으로만 사용.
- 카탈로그번호
- OSR00119W
- 판매단위
- pk
카탈로그
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 |
| Immunohistochemistry (IHC) | 1:1,000–1:2,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from mouse TAAR1 conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2303028 |
Product Specific Information
- This antibody is predicted to react with rat based on sequence homology.
- Reconstitute in 100 µL of sterile water.
Target Information
TA1 has been reported in human brain, dorsal root ganglion, olfactory bulb, kidney, liver, lung, pancreas, prostate, skeletal muscle, small intestine, spleen, spinal cord, and stomach.
An EST for TA1 has been identified from a human stomach cancer library.
G-protein Coupled Receptors (GPCRs) comprise one of the largest families of signaling molecules with more than a thousand members currently predicted to exist.
All GPCRs share a structural motif consisting of seven membrane-spanning helices and exist in both active and inactive forms.
An array of activating ligands participate in the conformation of GPCRs, leading to signaling via G-proteins and downstream effectors.
Ongoing studies have also shown the vast series of reactions which participate in the negative regulation of GPCRs.
This turn-off activity has tremendous implications for the physiological action of the cell and continues to drive pharmacological research for new drug candidates.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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