Thermo Fisher Scientific Phospho-Bcl-3 (Ser402) Polyclonal Antibody
Phospho-Bcl-3 (Ser402) 폴리클로날 항체로, 인간 BCL3 단백질의 Ser402 인산화 부위를 특이적으로 인식합니다. Western blot 및 IHC(P) 검증 완료. 1 mg/mL 농도의 액상 형태로, PBS와 50% 글리세롤에 보관되며 -20°C에서 안정적으로 저장됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human BCL3 (Accession P20749), corresponding to amino acid residues around phosphorylated Ser402. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2903271 |
Product Specific Information
This antibody detects endogenous levels of BCL-3 only when phosphorylated at Ser402.
Target Information
B cell Lymphoma 3 (Bcl-3) is a member of the IκB subfamily of inhibitors, which are part of the NF-κB transcription factor family. The balance of NF-κB family members regulates apoptosis and survival of activated T cells. Bcl-3 functions include cytoplasmic activation of p50 homodimers, nuclear translocation, and modulation of transcriptional machinery. Bcl-3 activity depends on nuclear interacting proteins such as Tip60, Jab1, Bard1, and Pirin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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