Thermo Fisher Scientific TPSG1 Polyclonal Antibody
TPSG1 단백질을 인식하는 Rabbit Polyclonal Antibody로, Human, Mouse, Rat 시료에 반응합니다. Western blot에 적합하며, 고순도(>95%)로 정제된 액상 제품입니다. 연구용으로만 사용되며 장기 보관 시 -20°C에서 보관합니다.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific TPSG1 Polyclonal Antibody
Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to residues in human TPSG1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2553988 |
Product Specific Information
- Detects endogenous TPSG1 protein at a molecular weight of 34 kDa.
- Purity is >95% by SDS-PAGE.
Target Information
Tryptase gamma, also known as serine protease 31 or transmembrane tryptase, is an enzyme encoded by the TPSG1 gene in humans. Tryptases belong to the trypsin-like serine protease family (peptidase family S1). They are enzymatically active only as heparin-stabilized tetramers and resistant to endogenous proteinase inhibitors.
Several tryptase genes are clustered on chromosome 16p13.3, with four functional genes identified: alpha I, beta I, beta II, and gamma I. Each has allelic variants (alpha II, beta III, gamma II). Beta tryptases are the main isoenzymes in mast cells, while alpha-tryptases predominate in basophils.
TPSG1 differs from other tryptase genes by having a C-terminal hydrophobic domain that may act as a membrane anchor. Tryptases are implicated in asthma and other allergic or inflammatory disorders.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.