Thermo Fisher Scientific NUP107 Polyclonal Antibody
NUP107 단백질을 표적하는 Thermo Fisher Scientific의 산양 유래 폴리클로날 항체입니다. Yeast에 반응하며 Western Blot에 적합합니다. 액상 형태로 제공되며 0.5 mg/mL 농도, -20°C 보관 조건을 가집니다. 연구용으로만 사용 가능합니다.
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Thermo Fisher Scientific NUP107 Polyclonal Antibody
Applications
- Western Blot (WB): 2–4 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Yeast |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence ELSPTYQTERFTK-C |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2933312 |
Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:8,000.
Target Information
The nuclear pore complex (NPC) is a protein assembly localized at the nuclear rim and mediates macromolecular transport between the nucleus and the cytoplasm. The mammalian nucleoporin (NUP107) is part of the hetero-oligomeric complex containing NUP160, NUP133, NUP96, and the mammalian homolog of yeast sec13p.
While most of the NUP107-160 sub-complex localizes to the nuclear pore, a small fraction is observed at kinetochores and pro-metaphase spindle poles in mitotic cells, associated with proteins such as Mad1, Mad2, Bub3, and Cdc20.
Immunodepletion of the NUP107-160 complex results in defective spindle assembly, indicating multiple functions. NUP107 has been identified as an HIV dependency factor (HDF), suggesting potential as a drug target in HIV treatment. Multiple isoforms of NUP107 are known to exist.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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