Thermo Fisher Scientific STX17 Polyclonal Antibody
STX17 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, IP 등 다양한 응용에 적합. 고순도 항원 친화 크로마토그래피 정제. 인간 시료 반응성, 액상 형태로 안정적 보관 가능.
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Thermo Fisher Scientific STX17 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 |
| Immunoprecipitation (IP) | 1–5 µL/mg of lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | E. coli-derived Human STX17 fragment |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Antigen affinity chromatography, Protein A |
| Storage Buffer | PBS, pH 7 |
| Contains | 0.03% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2902886 |
Target Information
SNAREs (soluble N-ethylmaleimide-sensitive factor-attachment protein receptors) are essential proteins for the fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion.
STX17 is a SNARE of the autophagosome involved in autophagy through the direct control of autophagosome membrane fusion with the lysosome membrane. STX17 may also play a role in the early secretory pathway, maintaining the architecture of the ER-Golgi intermediate compartment (ERGIC) and Golgi, and regulating transport between the endoplasmic reticulum, ERGIC, and Golgi. (Uniprot)
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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