Thermo Fisher Scientific STUB1 Polyclonal Antibody
STUB1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, ELISA, Immunoprecipitation 등에 적합. 항원 친화 크로마토그래피로 정제된 액상 형태. 인간 시료 반응성, 연구용으로 사용.
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Thermo Fisher Scientific STUB1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1:5,000–1:10,000 |
| Immunoprecipitation (IP) | 0.5–2 µL/mg of lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human STUB1 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Antigen affinity chromatography, Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2902884 |
Target Information
A recently identified protein, termed carboxyl terminus of hsc70-interacting protein (CHIP), interacts with both the constitutive form of hsc70 and the stress-inducible form, hsp70. This 35 kDa cytoplasmic protein is highly expressed in striated muscle and across a broad range of cultured tissues. Through immunoprecipitation experiments, CHIP has been shown to bind directly to the carboxyl terminus of hsc70 and hsp70, decreasing ATPase activity and reducing overall chaperone efficiency. CHIP also functions as an E3 ubiquitin ligase in the ubiquitin-proteasome system, containing a U-box domain and acting in conjunction with hsc70 and hsp90.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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