Thermo Fisher Scientific DNAL1 Polyclonal Antibody
Human DNAL1 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P) 및 ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며 PBS/glycerol buffer에 보관. PCD 및 HIV 연구용으로 적합한 연구용 항체.
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- PA562736
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- pk
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Thermo Fisher Scientific DNAL1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human DNAL1 (Recombinant protein control fragment Product #RP-100056) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term; for long-term storage, store at -20°C avoiding freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2640721 |
Product Specific Information
Immunogen sequence:
MAKATTIKEA LARWEEKTGQ RPSEAKEIKL YAQIPPIEKM DASLSMLANC EKLSLSTNCI EKIANLNGLK NLRILSLGRN NIKNLNGL
Highest antigen sequence identity to orthologs:
- Mouse: 94%
- Rat: 94%
Target Information
DNAL1 is a candidate gene for primary ciliary dyskinesia (PCD), a disorder characterized by chronic respiratory infections, randomization of body symmetry, and reduced fertility. It is expressed in tissues with motile cilia and interacts with DNAH5, regulating its activity in sperm flagella and respiratory cilia. DNAL1 has also been identified as an HIV dependency factor (HDF), suggesting potential relevance in HIV research. Two isoforms of DNAL1 are known.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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