Thermo Fisher Scientific SGPP1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (IHC)

1:200-1:500

-

Product Specifications

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human SGPP1 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:SGPP1,uniProtId:Q9BX95-1,ncbiNodeId:9606,antigenRange:385-416,antigenLength:441,antigenImageFileName:PA5-62741_SGPP1_Q9BX95-1_Rabbit.svg,antigenImageFileNamePDP:PA5-62741_SGPP1_Q9BX95-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2647219

Product Specific Information

Immunogen sequence: KITIPLACKI FNIPCDDIRK ARQHMEVELP YR

Highest antigen sequence identity to the following orthologs: Mouse - 84%, Rat - 81%.

Target Information

Sphingosine 1-phosphate (S1P) is a highly bioactive lipid that has a myriad of biological effects both intracellularly as a second messenger and extracellularly by binding to the S1P(1-5)/G-protein-coupled receptors of the endothelial differentiation gene family. Intracellularly, at least two enzymes, sphingosine kinase (1 and 2) and S1P phosphatase, regulate the activity of S1P by governing the phosphorylation of S1P. Regulation of hS1Pase1 with the resultant changes in cellular and secreted S1P has important implications in cell proliferation, angiogenesis and apoptosis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.