Thermo Fisher Scientific CTNNA3 Polyclonal Antibody
CTNNA3 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로널 항체로, 인간 및 생쥐 시료에 반응합니다. Western blot과 IHC(P) 등에 사용 가능하며, 액상 형태로 보존됩니다. 세포 접착 복합체 연구에 적합한 고품질 연구용 항체입니다.
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Thermo Fisher Scientific CTNNA3 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:1,000 | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within human CTNNA3 aa 30–70 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | TBS, pH 7.4, with 50% glycerol, 0.2% BSA |
| Contains | 0.05% sodium azide |
| Storage conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2913423 |
Product Specific Information
- Positive Control: NIH/3T3 cell lysates, Daudi cell lysates, mouse heart tissue
- Subcellular Location: Cytoskeleton
Target Information
Catenins are proteins that connect cadherin/beta-catenin cell adhesion complexes to the actin cytoskeleton. Although originally discovered in testis, alphaT-catenin is expressed in other tissues, with the highest levels observed in heart. Immunohistochemical analysis shows human alphaT-catenin localization at intercalated discs of cardiomyocytes and in peritubular myoid cells of testis. It has been demonstrated that alphaT-catenin can functionally restore cell-cell adhesion in colon cancer cells lacking alpha-catenins, indicating its involvement in forming specific cell-cell contacts in muscle cells. The encoded protein has a predicted size of approximately 100 kDa and shares about 57% amino acid identity with other alpha-catenins. In cells transfected with alphaT-catenin cDNA, interaction with alpha-catenin was confirmed by coimmunoprecipitation. The 892_24D2S antibody against alphaT-catenin does not cross-react with alphaE-catenin or alphaN-catenin in Western blot analysis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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