Thermo Fisher Scientific GBA2 Polyclonal Antibody
Thermo Fisher Scientific의 GBA2 Polyclonal Antibody는 인간 및 생쥐 시료에 반응하는 Rabbit IgG 항체로, Western blot과 ELISA에 적합합니다. 비결합형 액상 형태이며, 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 708–927 of human GBA2 (NP_0659951) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.87 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2805134 |
Product Specific Information
- Immunogen sequence: AQDIQDKFSS ILSRGQEAYE RLLWNGRYYN YDSSSRPQSR SVMSDQCAGQ WFLKACGLGE GDTEVFPTQH VVRALQTIFE LNVQAFAGGA MGAVNGMQPH GVPDKSSVQS DEVWVGVVYG LAATMIQEGL TWEGFQTAEG CYRTVWERLG LAFQTPEAYC QQRVFRSLAY MRPLSIWAMQ LALQQQQHKK ASWPKVKQGT GLRTGPMFGP KEAMANLSPE
- Positive Samples: U-87MG, Mouse kidney, Mouse heart
- Cellular Location: Cytoplasmic side, Endoplasmic reticulum membrane, Golgi apparatus membrane, Peripheral membrane protein
Target Information
Non-lysosomal glucosylceramidase that catalyzes the conversion of glucosylceramide (GlcCer) to free glucose and ceramide. Involved in sphingomyelin generation and prevention of glycolipid accumulation. May also catalyze the hydrolysis of bile acid 3-O-glucosides, though the relevance of such activity is unclear in vivo. Plays a role in central nervous system development and is required for proper formation of motor neuron axons.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일명: PA5-88792_GBA2_Q9HCG7-1_Rabbit_PDP.jpeg)
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