Thermo Fisher Scientific GBA2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 708-927 of human GBA2 (NP_0659951) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:GBA2,uniProtId:Q9HCG7-1,ncbiNodeId:9606,antigenRange:708-927,antigenLength:927,antigenImageFileName:PA5-88792_GBA2_Q9HCG7-1_Rabbit.svg,antigenImageFileNamePDP:PA5-88792_GBA2_Q9HCG7-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.87 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.01% thimerosal

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2805134

Product Specific Information

Immunogen sequence: AQDIQDKFSS ILSRGQEAYE RLLWNGRYYN YDSSSRPQSR SVMSDQCAGQ WFLKACGLGE GDTEVFPTQH VVRALQTIFE LNVQAFAGGA MGAVNGMQPH GVPDKSSVQS DEVWVGVVYG LAATMIQEGL TWEGFQTAEG CYRTVWERLG LAFQTPEAYC QQRVFRSLAY MRPLSIWAMQ LALQQQQHKK ASWPKVKQGT GLRTGPMFGP KEAMANLSPE; Positive Samples: U-87MG, Mouse kidney, Mouse heart; Cellular Location: Cytoplasmic side, Endoplasmic reticulum membrane, Golgi apparatus membrane, Peripheral membrane protein

Target Information

Non-lysosomal glucosylceramidase that catalyzes the conversion of glucosylceramide (GlcCer) to free glucose and ceramide. Involved in sphingomyelin generation and prevention of glycolipid accumulation. May also catalyze the hydrolysis of bile acid 3-O-glucosides, however, the relevance of such activity is unclear in vivo. Plays a role in central nevous system development. Required for proper formation of motor neuron axons.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.