Thermo Fisher Scientific ACACA Monoclonal Antibody (6H5)

Applications and Tested Dilution

Product Specifications

Product Specific Information

Sequence of this protein is as follows:
MWWSTLMSIL RARSFWKWIS TQTVRIIRAV RAHFGGIMDE PSPLAQPLEL NQHSRFIIGS VSEDNSEDEI SNLVKLDLLE EKEGSLSPAS VGSDTLSDL

Target Information

Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is regulated both long-term (transcriptional/translational) and short-term (phosphorylation/dephosphorylation and allosteric regulation by citrate or palmitoyl-CoA). Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified.

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.