Thermo Fisher Scientific ABL2 Monoclonal Antibody (3E4)
ABL2 단백질을 인식하는 Mouse monoclonal antibody(3E4)로 Western blot 및 ELISA에 사용 가능. Human 시료에 반응하며, 비결합형 액상 형태로 제공. PBS buffer(pH 7.4) 내 보존, -20°C에서 보관 권장.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| ELISA | 0.03 ng/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG3, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3E4 |
| Immunogen | ABL2 (AAH65912, 743–842 a.a) partial recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
KKTLGLRAGK PTASDDTSKP FPRSNSTSSM SSGLPEQDRM AMTLPRNCQR SKLQLERTVS TSSQPEENVD RANDMLPKKS EESAAPSRER PKAKLLPRGA
Target Information
ABL2 (Arg) is an Abl-related non-receptor protein tyrosine kinase that links cell surface receptors to cell proliferation and/or cytoskeletal reorganization.
Abl2 encodes a member of the Abelson family of nonreceptor tyrosine protein kinases. The protein is highly similar to the ABL1 protein, including the tyrosine kinase, SH2, and SH3 domains, and has a role in cytoskeletal rearrangements by its C-terminal F-actin- and microtubule-binding sequences.
ABL2 is expressed in both normal and tumor cells, and is involved in translocation with the ETV6 gene in leukemia. Multiple alternatively spliced transcript variants encoding different protein isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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