Thermo Fisher Scientific TPPP Recombinant Rabbit Monoclonal Antibody (JE47-35)
TPPP 단백질을 인식하는 재조합 토끼 단클론 항체로 Western blot, IHC, Flow cytometry에 적합. HEK293 세포에서 발현되며 Protein A로 정제. 인간 시료 반응성, 액상 형태, 고농도(1 mg/mL), 안정적 저장(-20°C, 암소 보관).
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Flow Cytometry (Flow) | 1:50–1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | JE47-35 |
| Immunogen | Recombinant protein within Human TPPP aa 80–185 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles, store in dark |
| Shipping Conditions | Wet ice |
| RRID | AB_2848759 |
Product Specific Information
Positive Control: Mouse brain tissue, rat brain tissue, human pancreas tissue, human uterus tissue, SHG-44.
Target Information
Tubulin family members are globular proteins important in the assembly of microtubules. Microtubules are structural components that play crucial roles in mitosis, cytokinesis, and vesicle transport.
TPPP (Tubulin polymerization-promoting protein), also known as p24 or p25, is a 219 amino acid protein localized in the perinuclear region of the cytoplasm. TPPP may form dimers and promote tubulin polymerization into double-walled tubules or stabilized aggregates.
Overexpression of TPPP can prevent mitotic spindle formation and nuclear envelope breakdown. It is phosphorylated by TPK II and encoded by a gene on human chromosome 5.
TPPP may contribute to microtubule polymerization, bundling, and stabilization, maintaining the integrity of the microtubule network and playing roles in mitotic spindle assembly and nuclear envelope breakdown.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(TPPP 관련 항원 이미지 및 구조 이미지가 포함됩니다.)
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