
Thermo Fisher Scientific Phospho-BAD (Ser99) Polyclonal Antibody
인간 BAD 단백질의 Ser99 인산화 부위를 인식하는 Rabbit Polyclonal Antibody. WB, IHC, ICC, ELISA 등 다양한 응용에 적합. 고순도 Protein A 정제, 액상 형태로 안정적 보관 가능. 연구용으로 세포 사멸 조절 기전 분석에 활용.
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Thermo Fisher Scientific Phospho-BAD (Ser99) Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | Assay-dependent |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic phosphopeptide derived from human BAD around the phosphorylation site of Ser99 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by BAD is a member of the BCL-2 family, known to regulate programmed cell death. BAD promotes apoptosis by forming heterodimers with BCL-xL and BCL-2, counteracting their anti-apoptotic function. Its proapoptotic activity is controlled by phosphorylation, involving kinases such as AKT and MAP kinase, and phosphatase calcineurin. Alternative splicing results in two transcript variants encoding the same isoform.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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