Thermo Fisher Scientific CD275 (B7-H2) Polyclonal Antibody
Mouse CD275(B7-H2) 단백질을 인식하는 Goat Polyclonal Antibody로, WB, IHC(F), ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS+trehalose 용액에 동결건조 형태로 제공. 비특이적 교차 반응이 낮고 연구용으로 적합.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.1 µg/mL | - |
| Immunohistochemistry (Frozen) (IHC (F)) | - | 1 publication |
| Immunocytochemistry (ICC/IF) | 5–15 µg/mL | 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Published Species | Mouse |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Mouse myeloma cell line NS0-derived recombinant mouse B7-H2 (Glu47–Lys279) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2577162 |
Product Specific Information
- In direct ELISAs and Western blots, less than 2% cross-reactivity with recombinant human (rh) B7-H2, recombinant mouse (rm) B7-1, rhB7-1, and rmB7-2 is observed.
- Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
Inducible co-stimulator ligand (ICOSL) is a specific ligand on antigen-presenting cells and peripheral tissue cells that binds to the inducible co-stimulator receptor (ICOS).
ICOS belongs to the CD28/CD152 receptor family that regulates T-cell activation and function.
ICOSL is expressed on monocytes, dendritic cells, and B cells, and can be induced by inflammatory stimuli in peripheral tissue.
Binding to ICOSL delivers a co-stimulatory signal for T-cell proliferation and cytokine secretion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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