Thermo Fisher Scientific CA3 Monoclonal Antibody (4A12-1A3)
CA3 단백질을 인식하는 Mouse IgG1 단클론 항체로, Western blot, IHC, ELISA 등 다양한 연구용 응용에 적합. Human 시료 반응성, 액상 형태, PBS buffer 보존. Affinity chromatography로 정제되어 높은 특이성과 재현성 제공.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 3 µg/mL |
| ELISA | 1 ng/mL |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4A12-1A3 |
| Immunogen | CA3 (AAH04897, 1–260 a.a.) full-length recombinant protein with GST tag (MW of GST tag: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Protein Sequence:
MAKEWGYASH NGPDHWHELF PNAKGENQSP IELHTKDIRH DPSLQPWSVS YDGGSAKTIL NNGKTCRVVF DDTYDRSMLR GGPLPGPYRL RQFHLHWGSS DDHGSEHTVD GVKYAAELHL VHWNPKYNTF KEALKQRDGI AVIGIFLKIG HENGEFQIFL DALDKIKTKG KEAPFTKFDP SCLFPACRDY WTYQGSFTTP PCEECIVWLL LKEPMTVSSD QMAKLRSLLP SAENEPPVPL VSNWRPPQPI NNRVVRASFK
Target Information
Carbonic anhydrase III (CAIII) is a member of a multigene family encoding carbonic anhydrase isozymes. These metalloenzymes catalyze the reversible hydration of carbon dioxide and are differentially expressed in various cell types.
CA3 gene expression is tissue-specific, highly expressed in skeletal muscle, and at lower levels in cardiac and smooth muscle. Elevated CA3 levels are observed in some carriers of Duchenne muscular dystrophy.
The CA3 gene spans approximately 10.3 kb and contains seven exons and six introns.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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