Thermo Fisher Scientific OTX2 Monoclonal Antibody (OTI3G9), TrueMAB
OTX2 단백질을 인식하는 마우스 단클론 항체로, Western blot에 적합합니다. 인간, 마우스, 랫트 반응성을 가지며, 동결건조 형태로 제공됩니다. 고순도 친화 크로마토그래피 정제 제품으로 연구용으로만 사용됩니다.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3G9 |
| Immunogen | Full-length human recombinant protein of human OTX2 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of about 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
OTX2 is a 289-amino-acid protein belonging to the bicoid sub-family of homeodomain transcription factors. It has two known splice variants and may have additional isoforms.
OTX2 acts as an early marker of endodermal differentiation in embryonic stem cells and contributes to brain and sensory organ development.
It binds to the BCD target sequence (BTS): 5'-TCTAATCCC-3'.
Defects in OTX2 are associated with microphthalmia syndromic type 5 (MCOPS5).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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