Thermo Fisher Scientific SGMS1 Polyclonal Antibody
Thermo Fisher Scientific SGMS1 Polyclonal Antibody는 인간 및 생쥐 시료에 반응하며 Western blot과 ELISA에 사용 가능합니다. 합성 펩타이드 항원 기반으로 제작된 Rabbit IgG 폴리클로날 항체로, PBS 버퍼에 0.08% sodium azide를 포함하며 -20°C에서 보관합니다. 연구용으로만 사용됩니다.
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- PA112761
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Thermo Fisher Scientific SGMS1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 5–10 µg/mL | View 1 publication |
| ELISA | Assay-dependent | – |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to human sphingomyelin synthase 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | PBS |
| Contains | 0.08% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2188419 |
Product Specific Information
A suggested positive control for this product is brain, heart, kidney, liver, muscle or stomach lysate.
Target Information
A bidirectional lipid cholinephosphotransferase capable of converting phosphatidylcholine (PC) and ceramide to sphingomyelin (SM) and diacylglycerol (DAG), and the inverse reaction.
The direction depends on the relative concentrations of DAG and ceramide as phosphocholine acceptors.
Directly and specifically recognizes the choline head group on the substrate. Requires two fatty chains on the choline-P donor molecule for efficient substrate recognition.
May not function strictly as a sphingomyelin synthase. Inhibited by bacterial PC-phospholipase C inhibitor D609.
Localized to Golgi apparatus; Golgi membrane; multi-pass membrane protein. Possibly present in brain, heart, kidney, liver, muscle, and stomach.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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