Thermo Fisher Scientific GCAP2 Polyclonal Antibody
Thermo Fisher Scientific의 GCAP2 Polyclonal Antibody는 인간 GUCA1B 단백질을 인식하는 토끼 다클론 항체입니다. Western blot 및 IHC(P) 실험에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000–1:2,500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human GUCA1B. Recombinant protein control fragment (Product #RP-108413). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2791407 |
Product Specific Information
Immunogen sequence:
GQEFSWEEAE AAGEIDVAEL QEWYKKFVME CPSGTLFMHE FKRFFKVTDD EEASQYVEGM FRAFDKNG
Target Information
Guanylate cyclase-activating proteins (GCAPs) are calcium-binding proteins belonging to the calmodulin superfamily. GCAPs without calcium activate photoreceptor guanylate cyclase during light adaptation. The addition or removal of Ca²⁺ induces conformational changes that regulate GCAP-1 and GCAP-2 activity. Both GCAP-1 and GCAP-2 act similarly on guanylate cyclase and share approximately 50% homology. GCAP-1 is predominantly localized in photoreceptor outer segments, while GCAP-2 is found in retina samples.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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