Thermo Fisher Scientific SCN11A Polyclonal Antibody
SCN11A 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. IHC에 적합하며 Mouse 종에 반응. 동결건조 형태로 보관 용이하며, 연구용으로 SCN11A 특이적 검출에 사용 가능.
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Thermo Fisher Scientific SCN11A Polyclonal Antibody
Applications
- Immunohistochemistry (IHC)
Tested Dilution: 1:300–1:2,000
Publications
- Miscellaneous PubMed: None
- View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from the internal region of mouse SCN11A conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity: SCN11A.
Target Information
Epithelial sodium channels are amiloride-sensitive members of the Degenerin/epithelial sodium channel (Deg/ENaC) superfamily of ion channels.
These channels possess two short intracellular amino and carboxyl termini, two short membrane spanning segments, and a large extracellular loop with a conserved cysteine-rich region.
There are three homologous isoforms of the ENaC (alpha, beta, and gamma) protein. ENaC in the kidney, lung, and colon plays a key role in sodium and fluid balance and is regulated partly through association with CFTR chloride ion channels.
Mutations in ENaC isoforms are associated with conditions such as Liddels syndrome and pseudohypoaldosteronism (PHA-1).
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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