Thermo Fisher Scientific Staphylococcus aureus LDHA Polyclonal Antibody
Staphylococcus aureus LDHA 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체입니다. Western blot에 적합하며, 4 mg/mL 농도의 액상 형태로 제공됩니다. Protein G로 정제되어 높은 특이성과 재현성을 제공합니다. 연구용으로만 사용 가능합니다.
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Thermo Fisher Scientific Staphylococcus aureus LDHA Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution
- 1:500–1:5,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bacteria |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Staphylococcus aureus L-lactate dehydrogenase 1 protein (1–317aa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 4 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.03% ProClin 300 |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Wet ice |
| RRID | AB_2902232 |
Product Specific Information
This antibody has been tested in direct-ELISA.
Target Information
Lactate dehydrogenase (LDH) is an enzyme in the glycolytic pathway that converts pyruvate to lactate with concomitant interconversion of NADH and NAD+. In mammals, the enzyme is encoded by three genes: LDHA (M or muscle form), LDHB (H or heart form), and LDHC (X or testis form).
The three human LDHs share 84–89% sequence similarities and 69–75% amino acid identities. There are five different LDH isoenzymes based on the proportion of M and H chains in the tetrameric structure.
LDHA is hypoxia-inducible and its expression is directly controlled by the transcriptional activity of hypoxia-inducible factor 1a (HIF1a). LDHB is also known to be upregulated in many cancers.
Mutations in the LDHA gene can lead to Glycogen Storage Disease 11 (GSD11).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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