Thermo Fisher Scientific FABP5 (Marker of Metastatic Potential in Colorectal Cancer) Recombinant Rabbit Monoclonal Antibody (FABP5/6353R)
인간 FABP5 단백질을 표적으로 하는 Thermo Fisher Scientific의 재조합 토끼 단일클론 항체. 대장암 전이 잠재력 마커 연구에 적합하며, WB, IHC, ICC 등 다양한 응용 가능. 고순도 Protein A/G 정제, 보존제 무첨가 PBS 용액 형태.
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Thermo Fisher Scientific FABP5 Recombinant Rabbit Monoclonal Antibody (FABP5/6353R)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 2–4 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | FABP5/6353R |
| Immunogen | Recombinant human full-length FABP5 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
FABP5 (fatty acid binding protein 5, psoriasis-associated) is a cytoplasmic protein encoded by the FABP5 gene, also known as PAFABP, EFABP, E-FABP, KFABP, PA-FABP.
It belongs to a family of small, highly conserved proteins that bind long-chain fatty acids and other hydrophobic ligands. The PAFABP cDNA encodes a 135-amino acid protein with a molecular weight of approximately 15,164 Da.
FABP5 is primarily found in epidermal cells and was first identified as being upregulated in psoriasis tissue. It plays a key role in fatty acid uptake, transport, and metabolism.
According to Kaczocha et al. (2009), FABP5 and FABP7 transport AEA from the plasma membrane to subcellular fatty acid amide hydrolase, where AEA is hydrolyzed and inactivated, whereas FABP3 does not show this specific transport function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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