Thermo Fisher Scientific FABP5 (Marker of Metastatic Potential in Colorectal Cancer) Recombinant Rabbit Monoclonal Antibody (FABP5/6353R)
인체 FABP5 단백질을 인식하는 재조합 토끼 단클론 항체로, 대장암 전이 잠재력 마커 연구에 적합합니다. Western blot, IHC, ICC 등 다양한 응용에 사용 가능하며, 고순도 Protein A/G 정제 및 안정한 PBS 기반 보존 용액으로 제공됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 2–4 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | FABP5/6353R |
| Immunogen | Recombinant human full-length FABP5 protein (UniProt ID: Q01469-1, amino acids 1–135) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
FABP5 (fatty acid binding protein 5, psoriasis-associated) is a small, highly conserved cytoplasmic protein encoded by the FABP5 gene. It binds long-chain fatty acids and other hydrophobic ligands, playing roles in fatty acid uptake, transport, and metabolism.
The protein consists of 135 amino acids (molecular weight ~15.2 kDa) and is highly expressed in epidermal cells, originally identified as upregulated in psoriasis tissue.
Kaczocha et al. (2009) identified FABP5 and FABP7 as cytosolic transporters of anandamide (AEA) to fatty acid amide hydrolase for hydrolysis and inactivation. FABP3 did not show this specific transport function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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