Thermo Fisher Scientific HP1 beta Polyclonal Antibody
Human HP1 Beta/CBX1 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체. Western blot, ICC/IF, IP 등 다양한 응용에 적합. 보존제 무첨가로 고순도, 장기보관 시 -20°C 권장. 연구용으로만 사용 가능.
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Thermo Fisher Scientific HP1 beta Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:300–1:10,000 |
| Immunoprecipitation (IP) | 0.5–2 µL/mg of lysate |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to the center region of Human CBX1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C avoiding freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2788388 |
Product Specific Information
This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
This antibody has specificity for Human HP1 Beta/CBX1.
Target Information
The HP1 Beta (CBX1) gene encodes a highly conserved nonhistone protein belonging to the heterochromatin protein family. It is enriched in heterochromatin and associated with centromeres.
The protein contains:
- N-terminal chromodomain: binds to histone proteins via methylated lysine residues
- C-terminal chromo shadow-domain: responsible for homodimerization and interaction with chromatin-associated nonhistone proteins
HP1 Beta may play an important role in epigenetic control of chromatin structure and gene expression. Several related pseudogenes are located on chromosomes 1, 3, and X. Multiple alternatively spliced variants encoding the same protein have been identified.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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