Thermo Fisher Scientific TG Monoclonal Antibody (OTI8B5), TrueMAB
인간 Thyroglobulin(TG)을 인식하는 단클론 항체로, IHC(P) 검증 완료. 마우스 IgG1 아이소타입이며, 동결건조 형태로 제공. 연구용으로만 사용 가능하며, 항체 재구성 및 결합 실험에 적합.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): Tested dilution 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI8B5 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 20–358 of human TG produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Human thyroglobulin (hTg) is a high molecular weight glycoprotein (605 kDa) found in thyroid follicular cells. It plays a central role in the uptake, incorporation, and regulated biosynthesis of thyroid hormones T4 and T3.
Anti-thyroglobulin autoantibodies are associated with autoimmune thyroid diseases such as Hashimoto thyroiditis and Graves’ disease, with the highest levels found in Hashimoto thyroiditis.
Anti-hTG is also characteristic of thyroid cancer and can be used for monitoring patients after treatment.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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