Thermo Fisher Scientific RASA1 Monoclonal Antibody (OTI4E2), TrueMAB
RASA1 단백질을 인식하는 Mouse monoclonal 항체로 Western blot 및 Immunocytochemistry에 적합. Human 시료 반응성. 고순도 Affinity chromatography 정제, PBS/BSA/glycerol buffer에 보존. 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4E2 |
| Immunogen | Full length human recombinant protein of human RASA1 produced in HKE293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
TACC1 is located on 8p11 chromosomal region that is amplified in approximately 15% of all breast tumor samples. The short arm of chromosome 8 also contains FGFR1 whose expression is enhanced in most breast cancer tumors. TACC family members, TACC1, TACC2, and TACC3, map very closely to the corresponding FGFR1, FGFR2, FGFR3 genes on chromosomes 4, 8, and 10. Since they are phylogenetically related, it is proposed that TACC and FGFR have similar roles in cell growth and differentiation. TACC1 contains a conserved C-terminal region as in the Drosophila homolog D-TACC, which is necessary for normal spindle function, and mammalian TACC proteins appear to interact with centrosomes and microtubules in a similar manner.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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