Thermo Fisher Scientific CAMK2B Monoclonal Antibody (6D6)
CAMK2B 단백질을 인식하는 Mouse 모노클로날 항체(클론 6D6). Western blot, ICC/IF, ELISA 등 다양한 응용 가능. 인간 시료에 반응하며, 액상 형태로 제공. 연구용으로만 사용 가능.
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Thermo Fisher Scientific CAMK2B Monoclonal Antibody (6D6)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| Immunocytochemistry (ICC/IF) | 25 µg/mL |
| ELISA | 10 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 6D6 |
| Immunogen | CAMK2B (NP_742078, 405–502 a.a.) partial recombinant protein with GST tag (MW of GST tag: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
FEPEALGNLV EGMDFHRFYF ENLLAKNSKP IHTTILNPHV HVIGEDAACI AYIRLTQYID GQGRPRTSQS EETRVWHRRD GKWQNVHFHC SGAPVAPL
Target Information
CAMK2B (CaMKII beta) is a serine/threonine kinase involved in synaptic plasticity, synaptic vesicle mobilization, and regulation of gene expression. It functions as a dominant kinase in the central nervous system, contributing to long-term potentiation and neurotransmitter release.
There are four CaMKII isozymes—alpha, beta, gamma, and delta—which may be co-expressed in the same tissue. CaMKII alpha is autophosphorylated on Thr 286 upon Ca2+/CaM complex binding to its autoinhibitory domain, a process known as Ca2+/CaM trapping, implicated in synaptic information encoding.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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