Thermo Fisher Scientific CAMK2B Monoclonal Antibody (S13)
CAMK2B 단백질을 인식하는 S13 클론의 Mouse 모노클로날 항체. Western blot 및 ELISA에 적합. 인간 반응성, 비결합형 액상 형태로 제공. 신경계 내 시냅스 가소성과 유전자 발현 연구에 활용 가능.
- 카탈로그번호
- H00000816-M07
- 판매단위
- pk
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Thermo Fisher Scientific CAMK2B Monoclonal Antibody (S13)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| ELISA | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | S13 |
| Immunogen | CAMK2B (AAH19070.1, 1 a.a. ~503 a.a) full-length recombinant protein with GST tag (MW of GST tag: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MATTVTCTRF TDEYQLYEDI GKGAFSVVRR CVKLCTGHEY AAKIINTKKL SARDHQKLER EARICRLLKH SNIVRLHDSI SEEGFHYLVF DLVTGGELFE DIVAREYYSE ADASHCIQQI LEAVLHCHQM GVVHRDLKPE NLLLASKCKG AAVKLADFGL AIEVQGDQQA WFGFAGTPGY LSPEVLRKEA YGKPVDIWAC GVILYILLVG YPPFWDEDQH KLYQQIKAGA YDFPSPEWDT VTPEAKNLIN QMLTINPAKR ITAHEALKHP WVCQRSTVAS MMHRQETVEC LKKFNARRKL KGAILTTMLA TRNFSAAKSL LNKKADGVKP QTNSTKNSAA ATSPKGTLPP AALESSDSAN TTIEDEDAKA RKQEIIKTTE QLIEAVNNGD FEAYAKICDP GLTSFEPEAL GNLVEGMDFH RFYFENLLAK NSKPIHTTIL NPHVHVIGED AACIAYIRLT QYIDGQGRPR TSQSEETRVW HRRDGKWQNV HFHCSGAPVA PLQ
Target Information
CAMK2B (CaMKII beta) is a serine/threonine kinase that plays a role in synaptic plasticity, synaptic vesicle mobilization, and regulation of gene expression. As a dominant kinase in the central nervous system, it may function in long-term potentiation and neurotransmitter release.
There are four CaMKII isozymes (alpha, beta, gamma, delta), which may or may not be co-expressed in the same tissue type. CaMKII alpha is autophosphorylated on Thr 286 upon Ca²⁺/CaM complex binding to its autoinhibitory domain, a process known as Ca²⁺/CaM trapping, involved in synaptic information encoding.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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