Thermo Fisher Scientific CAMK2B Monoclonal Antibody (S13)

Thermo Fisher Scientific CAMK2B Monoclonal Antibody (S13)

Applications and Tested Dilution

Product Specifications

Product Specific Information

Sequence of this protein is as follows:
MATTVTCTRF TDEYQLYEDI GKGAFSVVRR CVKLCTGHEY AAKIINTKKL SARDHQKLER EARICRLLKH SNIVRLHDSI SEEGFHYLVF DLVTGGELFE DIVAREYYSE ADASHCIQQI LEAVLHCHQM GVVHRDLKPE NLLLASKCKG AAVKLADFGL AIEVQGDQQA WFGFAGTPGY LSPEVLRKEA YGKPVDIWAC GVILYILLVG YPPFWDEDQH KLYQQIKAGA YDFPSPEWDT VTPEAKNLIN QMLTINPAKR ITAHEALKHP WVCQRSTVAS MMHRQETVEC LKKFNARRKL KGAILTTMLA TRNFSAAKSL LNKKADGVKP QTNSTKNSAA ATSPKGTLPP AALESSDSAN TTIEDEDAKA RKQEIIKTTE QLIEAVNNGD FEAYAKICDP GLTSFEPEAL GNLVEGMDFH RFYFENLLAK NSKPIHTTIL NPHVHVIGED AACIAYIRLT QYIDGQGRPR TSQSEETRVW HRRDGKWQNV HFHCSGAPVA PLQ

Target Information

CAMK2B (CaMKII beta) is a serine/threonine kinase that plays a role in synaptic plasticity, synaptic vesicle mobilization, and regulation of gene expression. As a dominant kinase in the central nervous system, it may function in long-term potentiation and neurotransmitter release.
There are four CaMKII isozymes (alpha, beta, gamma, delta), which may or may not be co-expressed in the same tissue type. CaMKII alpha is autophosphorylated on Thr 286 upon Ca²⁺/CaM complex binding to its autoinhibitory domain, a process known as Ca²⁺/CaM trapping, involved in synaptic information encoding.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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