Thermo Fisher Scientific CDC45 Monoclonal Antibody (OTI8A1), TrueMAB
인간 CDC45 단백질을 타깃으로 한 마우스 단클론 항체입니다. Western blot에 최적화되어 있으며, 1:500 희석 비율로 검증되었습니다. 고순도의 Affinity chromatography 정제 항체로, PBS/BSA/glycerol 완충액에 보관됩니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- TA811269
- 판매단위
- pk
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Applications
- Western Blot (WB): Tested dilution 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI8A1 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–270 of human CDC45 produced in E. coli. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by this gene was identified by its strong similarity with Saccharomyces cerevisiae Cdc45, an essential protein required for the initiation of DNA replication.
Cdc45 is part of a conserved multiprotein complex including Cdc6/Cdc18, MCM proteins, and DNA polymerase, critical for early steps of DNA replication in eukaryotes.
This protein interacts with MCM7 and DNA polymerase alpha, and studies in Xenopus suggest it plays a pivotal role in loading DNA polymerase alpha onto chromatin.
Multiple polyadenylation sites of this gene are reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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