Thermo Fisher Scientific Phospho-Nociceptin/Orphanin FQ Receptor (Ser351) Polyclonal Antibody
인간, 생쥐, 랫트 반응성의 Ser351 인산화 부위 특이 폴리클로날 항체. Western blot에 적합하며 항원 친화 크로마토그래피로 정제됨. 액상 형태로 제공되며 장기 보관 시 -20°C에서 보관 권장. 연구용으로만 사용 가능.
- 판매단위
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Applications
- Western Blot (WB): Tested dilution 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic phosphopeptide derived from human NOP around the phosphorylation site of Ser351 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Dulbecco’s PBS, pH 7.4 |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice (domestic); Dry ice (international) |
Target Information
The G-protein-coupled receptor (GPCR) superfamily is comprised of an estimated 600–1,000 members and represents the largest known class of molecular targets with therapeutic relevance.
The nociceptin receptor is a G-protein coupled opioid receptor that binds the endogenous neuropeptide nociceptin. Ligand binding induces conformational changes that trigger G protein-mediated signaling, inhibiting adenylate cyclase and calcium channel activity. Arrestins modulate G protein signaling and activate alternative pathways, including MAP kinase activation.
This receptor plays a key role in modulating nociception, pain perception, and locomotor activity regulation by nociceptin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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